Hydrophilic dispersions of nanoparticles of inclusion complexes of salicylic acid
AssigneeSoluBest Ltd.
InventorsRina Goldshtein, Vadim Goldshtein, Vladimir Mikunis, Larisa Gitis
Life of this patent
Estimating the term…
Abstract
The invention provides a hydrophilic inclusion complex consisting essentially of nanosized particles of salicylic acid wrapped in an amphiphilic polymer, wherein said amphiphilic polymer is selected from the group consisting of polyacrylic acid, polyacrylamide and copolymers thereof, polymethacrylamide and copolymers thereof, and polylysine, and said amphiphilic polymer is modified by reaction with urea or a derivative thereof, nicotinamide or guanidine. Further provided are hydrophilic dispersions comprising nanoparticles of said inclusion complexes and pharmaceutical and cosmetic compositions comprising said dispersions.
Claims20
A hydrophilic inclusion complex consisting essentially of nanosized particles of salicylic acid wrapped in an amphiphilic polymer such that non-valent bonds are formed between the salicylic acid and the amphiphilic polymer, wherein said amphiphilic polymer is selected from the group consisting of polyacrylic acid, polyacrylamide and copolymers thereof, polymethacrylamide and copolymers thereof, and polylysine, and said amphiphilic polymer is modified by reaction with urea or a derivative thereof, nicotinamide or guanidine.
A hydrophilic dispersion comprising nanoparticles of inclusion complexes of salicylic acid wrapped in an amphiphilic polymer such that non-valent bonds are formed between the salicylic acid and the amphiphilic polymer, wherein said amphiphilic polymer is selected from the group consisting of polyacrylic acid, polyacrylamide and copolymers thereof, polymethacrylamide and copolymers thereof, and polylysine, and said amphiphilic polymer is modified by reaction with urea or a derivative thereof, nicotinamide or guanidine.
Dependencies are inferred from the claim text.