Non-vesicular cationic lipid formulations
OwnerHeinrich Haas, Toralf Peymanninventors
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Abstract
The present invention relates to a non-vesicular preparation comprising at least one cationic amphiphile in an aqueous environment, its production and use and a cationic liposome suspension obtainable thereof with increase drug trap ratio and its areas of application such as pharmacology and medicine, particularly its use as carrier system for active substances.
Claims25
1-22. (canceled)
A non-vesicular preparation comprising at least one cationic amphiphile in a concentration of about 10 mM to about 600 mM with a mean chain length from C12 to C24, optionally at least one further amphiphile of up to about 60 mol % based on the total amphiphile concentration and optionally at least one stabilizing agent in a concentration of about 10 mM to about 600 mM in an aqueous phase, wherein said preparation is characterized by being transparent, isotropic and substantially homogeneous.
Dependencies are inferred from the claim text.