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US 2005/0191694 A1Published application
Clinically intelligent diagnostic devices and methods
AssigneeIntelligent Medical Devices, Inc., a Delaware corporation
InventorsAlice Jacobs, Vineet Gupta, Boris Nikolic
Life of this patent
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Abstract
The invention relates to the clinically intelligent design of diagnostic devices (such as microarrays) and methods of making and using such devices in differential diagnoses of specific clinical symptoms or sets of symptoms. In one aspect, the devices include various probes used to perform parallel screening of a number of analytes. The probes are clustered on the devices based on known clinical presentations of symptoms associated with specific diseases and disorders.
Claims12
1-23. (canceled)
A device comprising:
- (a) a substrate having a surface, wherein the surface comprises a plurality of protrusions having top surfaces;
- and
- (b) an array of probes or sets of probes, wherein each probe or set of probes selectively interacts with a unique target, and is attached to the top surface of one of the protrusions.
A device comprising:
- (a) a substrate having a surface, wherein the surface comprises multiple wells, each well comprising a micromixer;
- (b) a micromotor connected to each micromixer;
- and
- (c) an array of probes or sets of probes, wherein each probe or set of probes in the array selectively interacts with a unique target and is attached within one of the wells.
1 more element
A device comprising:
- (a) a substrate having a surface;
- (b) an array of probes or sets of probes, wherein each probe or set of probes in the array specifically binds to a unique target;
- and
- (c) an set of linkers, wherein the linkers bind the probes to the surface, and wherein the linkers have different lengths.
1 more element
Dependencies are inferred from the claim text.