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US 2005/0180963 A1Published application
Probiotic propionibacterium
AssigneeUniversity of Newcastle Research Associates (TUNRA) Ltd.
InventorsMichelle Adams, Yang Huang
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AssigneeUniversity of Newcastle Research Associates (TUNRA) Ltd.
InventorsMichelle Adams, Yang Huang
Estimating the term…
The present invention relates to probiotic Propionibacterium strains and their use in the preparation of probiotic supplements and foods. The invention relates to the provision of Vitamin B12, propionic acid, folacin and bacteriocins by probiotic strains, stimulation of bifidobacteria growth, production of favourable effects on the lipid metabolism and on the immune system of hosts through immunostimulation, immunomodulation or use of a probiotic strain as an adjuvant, reduction of homocysteine and β glucuronidase and the prevention, treatment or amelioration of conditions associated with a need for these activities. The probiotic bacteria of the invention can be used in humans or other animals. In at least some applications, the bacteria can be used dead and parts rather than whole cells may be used. The present invention also relates to the preparation of vaccines for use in protecting patients from infectious diseases, in particular tuberculosis.
An isolated Propionibacterium strain Propionibacterium jensenii 702.
A formulation comprising Propionibacterium jensenii 702 together with a culture medium, storage medium excipient, carrier or diluent.
(canceled)
A Vitamin B12 supplement comprising Propionibacterium jensenii 702 together with a delivery agent.
A growth promotor for animal feed comprising Propionibacterium jensenii 702 together with a suitable carrier, excipient or diluent.
A method of preventing food spoilage, extending the shelf life of food products, or both comprising preparing the food by including a fermentation step involving use of Propionibacterium jensenii 702.
A method of preventing food spoilage, extending the shelf life of food products, or both, comprising preparing the food by including a fermentation step involving use of Propionibacterium jensenii 702 in mixed culture with another food fermentation microorganism.
A food prepared using Propionibacterium jensenii 702 or parts thereof
A method of preparing a food comprising using Propionibacterium jensenii 702 or parts thereof in the preparation.
A mixed culture of Propionibacterium jensenii 702 with one or more other probiotic bacteria.
A method for protecting a probiotic microorganism during passage through the gastrointestinal tract which method comprises administering the probiotic in the presence of a soy or cereal based product.
A mucosal vaccine for tuberculosis comprising an antigen comprising at least one cellular or secreted protein of Mycobacterium tuberculosis or at least one immunologically active part thereof together with a mucosal adjuvant.
44-51. (canceled)
An isolated Mycobacterium tuberculosis antigen comprising at least one cellular or secreted protein of Mycobacterium tuberculosis or at least one immunologically active part thereof.
(canceled)
An isolated Mycobacterium antigen comprising at least one cellular or secreted protein of a Mycobacterium species or at least one immunologically active part thereof.
Dependencies are inferred from the claim text.