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US 2005/0101619 A1Published application
Anti-picornaviral compounds
AssigneePresident and Fellows of Harvard College
InventorsSimon Tsang, Diane Joseph-McCarthy, James Hogle
Life of this patent
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Abstract
The present invention is broadly directed to methods of screening viral-binding compounds. In particular, the present invention provides cell-free assays to rapidly screen libraries of compounds for viral-capsid binding activity. Such compounds are useful for anti-viral treatments.
Claims13
A compound represented by the molecular formulas comprising:
- a)
- wherein
- i) R1 is
- and
- R2 is selected from the group consisting of
- ii) R1 is
- and
- R2 is
- iii) R1 is
- and
- R2 is selected from the group consisting of
- b)
- wherein
- i) R3 is
- and
- R4 is selected from the group consisting of
- ii) R3 is
- R4 is
- iii) R3 is
- R4 is selected from the group consisting of
17 more elements
Dependencies are inferred from the claim text.