Using multiple perturbations to elucidate connectivity in network systems
OwnerJoseph Lehar, Raymond Molnar +2inventors
InventorsJoseph Lehar, Raymond Molnar, Curtis Keith, Grant Zimmermann
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OwnerJoseph Lehar, Raymond Molnar +2inventors
InventorsJoseph Lehar, Raymond Molnar, Curtis Keith, Grant Zimmermann
Estimating the term…
One embodiment of the invention is a method of analyzing the effects of combined perturbers of a network system by means of a set of model predictions for various network configurations, using a set of phenomenologically-based combination surface models. This method can be used to predict the effects of combined perturbers of known networks, for example, providing mechanistic validation for therapeutic compounds. Alternatively, this method can provide constraints for constructing connectivity models from observed combination effects on networks of unknown structure, thus, for example, providing the required understanding to identify novel targets for therapeutic compounds.
A method of elucidating connectivity in a network system that has been subjected to a plurality of agents, the agents having an interaction in the system, the method comprising:
A method of elucidating connectivity in a network system that has been subjected to a plurality of agents, the method comprising:
A computer program product for use on a computer system for elucidating connectivity in a network system from an interaction of agents, the computer readable program code including:
A method of producing an interaction model to describe an interaction of agents in a network system for elucidating connectivity in the system, the method comprising:
Dependencies are inferred from the claim text.