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US 2005/0090481 A1Published application
Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment
AssigneeQLT Inc.
InventorsRonald Boch, Peter Lutwyche, John North, Wendy Monk
Life of this patent
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Abstract
The present invention relates to a composition comprising a photosensitizing agent and a skin-penetration enhancer. The composition herein show improved delivery of the photosensitizer through the stratum corneum. In addition, the composition of the present invention show improved stability and a reduced incidence of skin photosensitivity.
Claims20
A composition comprising:
- a photosensitizer and a skin-penetration enhancer.
A composition comprising green-porphyrin photosensitizer, low molecular weight polyethylene glycol, diethylene glycol monoethyl ether, high molecular weight polyethylene glycol, and fatty alcohol.
A method of photodynamic therapy comprising:
- (i) applying to the skin a composition comprising a photosensitizing agent and a carrier wherein the carrier comprises a skin-penetration enhancer,
- (ii) allowing time for at least some of the photosensitizer to penetrate through the stratum corneum,
- (iii) washing the skin to which the composition has been applied, and
- (iv) irradiating with activation energy at a wavelength appropriate to activate the photo sensitizer.
1 more element
Dependencies are inferred from the claim text.