Elongase gene and production of delta9-polyunsaturated fatty acids
OwnerJohnathan Napier, Colin Lazarus +2inventors
InventorsJohnathan Napier, Colin Lazarus, Baoxiu Qi, Jens Lerchl
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OwnerJohnathan Napier, Colin Lazarus +2inventors
InventorsJohnathan Napier, Colin Lazarus, Baoxiu Qi, Jens Lerchl
Estimating the term…
This invention relates to a new elongase gene having the sequence SEQ ID NO: 1 or its derivatives, to a gene construct comprising this sequence or its derivatives and to its use. The inventive nucleic acid sequence encodes a polypeptide which elongates α-linolenic acid (C18:3 d9, 12, 15) by at least two carbon atoms whereas γ-linolenic acid (C18:3 d6, 9, 12) is not elongated. The invention additionally relates to vectors or organisms comprising an elongase gene having the sequence SEQ ID NO: 1 or its derivatives. The invention further relates to a process for the production of polyunsaturated fatty acids (=PUFAs) with an organism which comprises the elongase gene and which organism produces high amounts of oils and especially oils with a high content of unsaturated fatty acids. Additionally the invention relates to an oil and/or fatty acid composition with a higher content of polyunsaturated C20 or C22 fatty acids with at least two double bonds and/or to a triacylglycerol composition with a higher content of said polyunsaturated fatty acids.
An isolated nucleic acid derived from a plant encoding a polypeptide which elongates α-linolenic acid (C18:3 d9, 12, 15) by at least two carbon atoms whereas γ-linolenic acid (C18:3 d6, 9, 12) is not elongated.
An isolated nucleic acid comprising a nucleotide sequence which encodes a polypeptide which elongates α-linolenic acid (C18:3 d9, 12, 15) by at least two carbon atoms whereas γ-lino-lenic acid (C18:3 d6, 9, 12) is not elongated, selected from the group consisting of
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