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US 2005/0089953 A1Published application
Bioarray chip reaction apparatus and its manufacture
AssigneeAffymetrix, Inc.
InventorsDonald Besemer, Virginia Goss, James Winkler
Life of this patent
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Abstract
A body 300 having a cavity 310 for mounting a substrate 120 fabricated with probe sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, is provided. The cavity includes inlets 350 and 360 for introducing selected fluids into the cavity to contact the probes. Accordingly, a commercially feasible device for use in high throughput assay systems is provided.
Claims2
A method of making probe chips comprising the steps of:
- forming a plurality of probe arrays on a wafer;
- separating said wafer into a plurality of chips, each of said chips comprising at least one probe array thereon;
- and
- mating at least one of said chips to a package, said package comprising a reaction chamber, said reaction chamber comprising inlets for flowing fluid therein, said at least one probe array in fluid communication with said reaction chamber.
1 more element
2-92. (canceled).
Dependencies are inferred from the claim text.