Methods for determining and measuring risk of arteriosclerotic disease, microarray, apparatus and program for determining risk of arteriosclerotic disease

A method for detecting genetic polymorphisms comprising a process for detecting a genotype of a subject on genetic polymorphisms constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 9-1 and 9-2,

• wherein the detection result is used for determining the risk of arteriosclerotic disease.

A method for detecting genetic polymorphisms comprising a process for detecting a genotype of a subject on genetic polymorphisms constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 1-1, 1-2, 1-3 and 1-4,

• wherein the detection result is used for determining the risk of arteriosclerotic disease.

A genetic marker comprising genetic polymorphisms constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from

• the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 9-1 and 9-2.

A genetic marker comprising genetic polymorphisms constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from

• the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 1-1, 1-2, 1-3 and 1-4.

A kit for analyzing genetic polymorphisms comprising a pair of primers capable of specifically amplifying genes constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 9-1 and 9-2 or a nucleic acid probe capable of specifically hybridizing the genes,

• wherein the kit is so configured as to detect at least one of the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 9-1 and 9-2.

A kit for analyzing genetic polymorphisms comprising a pair of primers capable of specifically amplifying genes constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 1-1, 1-2,1-3 and 1-4 or a nucleic acid probe capable of specifically hybridizing the genes,

• wherein the kit is so configured as to detect at least one of the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 1-1, 1-2, 1-3 and 1-4.

An array for determining the risk of arteriosclerotic disease comprising a probe for detecting genetic polymorphisms constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 9-1 and 9-2.

An array for determining the risk of arteriosclerotic disease comprising a probe for detecting genetic polymorphisms constituting at least one set of arteriosclerosis-associated genetic polymorphisms selected from the sets of arteriosclerosis-associated genetic polymorphisms shown in Tables 1-1, 1-2,1-3 and 1-4.

An apparatus for determining the risk of arteriosclerotic disease using a computer, comprising:

• a data table on the risk of arteriosclerosis in which combinations of plural genetic polymorphisms are listed with corresponding risks of arteriosclerosis, and
• detection means for checking inputted combinations of plural genetic polymorphisms of a subject against the combinations of plural genetic polymorphisms in the data table on the risk of arteriosclerosis and, when there is a combination of genetic polymorphisms matching between the two, detecting the risk of arteriosclerosis corresponding to the combination of genetic polymorphisms.