Method of performing array-based hybridization assays using thermal inkjet deposition of sample fluids
OwnerMichael Caren, Kevin Luebkeinventors
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Abstract
Methods are provided for depositing a quantity of fluid onto the surface of an array. In the subject methods, a thermal inkjet head loaded with the fluid is positioned in opposing relationship to, e.g. over, the array surface. Actuation of the thermal ink-jet results in the expulsion of a quantity of fluid onto the array surface. The subject methods find particular use in array-based binding assays in which an array of binding agents is employed for the detection of an analyte(s), particularly array-based hybridization assays.
Claims11
1-21. (canceled)
A method for screening a fluid sample at least suspected of containing an analyte, comprising:
- positioning an inkjet head filled with a fluid in opposing relation to an array surface comprising a plurality of binding agents stably associated therewith;
- and
- actuating the inkjet head in a manner sufficient to expel said fluid onto a location on the array substrate comprising a binding agent;
- detecting a specific binding interaction between the binding agent and an analyte in said fluid.
Dependencies are inferred from the claim text.