Transdermal therapeutic system which contains a D2 agonist and which is provided for treating parkinsonism, and a method for the production thereof
AssigneesLTS Lohmann Therapie-Systeme AG, Aderis Pharmaceuticals, Inc.
InventorsWalter Mueller, James Peck
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Abstract
A substantially solvent-free matrix layer containing (−)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino]-1-naphthalenol is produced by adding an active substance to an adhesive solution, coating the resultant active substance-containing adhesive solution onto a suitable sheet, and removing the solvents in a drying process to give said substantially solvent-free matrix layer.
Claims16
A method for the manufacturing of a substantially solvent-free matrix layer containing (−)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino]-1-naphthalenol, said method comprising:
- a) adding an active substance to an adhesive solution,
- b) coating the resultant active substance-containing adhesive solution onto a sheet, and
- c) removing the solvents in a drying process to give said substantially solvent-free matrix layer.
Dependencies are inferred from the claim text.