Functionalized polymeric media for separation of analytes
AssigneeMallinckrodt Inc.
InventorsNandkumar Deorkar, James Farina, Paul Bouis
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Abstract
Separation of a variety of analytes that are polar, nonpolar and ionic using functionalized polymeric media is disclosed. Preformed rigid particles of highly crosslinked homopolymer of polyvinylidene compounds are functionalized using the residual vinyl groups onto which monovinyl compounds are covalently bonded through polymerization. The functionalization imparts desirable surface properties for separation applications such as liquid chromatography and solid phase extraction.
Claims48
Functionalized polymer beads prepared by
- a) polymerizing a polyvinylidene monomer to form a self-crosslinked homopolymer;
- and then
- b) polymerizing a functional monomer to covalently bond to said homopolymer.
A method for preparing a functionalized polymer bead, said method comprising the steps of:
- a) polymerizing a polyvinylidene monomer to form a homopolymer, and then
- b) polymerizing a functional monomer which covalently binds to said homopolymer.
Dependencies are inferred from the claim text.