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OwnerYalcin Cetin, Yuksel Savasinventors
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The invention relates to the use of a guanylate cyclase C activated peptide for the treatment of respiratory airway problems and problems associated with ventilation disorder and/or mucous secretion disorders via the airways, in addition to a medicament which is fed via the airways. The invention also relates to an inhalation device which contains the medicament and a method for diagnosing the illnesses associated with inhalation disorders and mucous secretion disorders in the airways, by detecting a gualylate cyclase C activated peptide. The peptides which are used are guanylin, uroguanylin and lymphoguanylin or a heat resistant enterotoxin.
The use of a peptide which activates guanylate cyclase C for producing a medicament for the treatment of respiratory tract disorders and disorders associated with impairments of ventilation and/or impairments of mucus secretion via the airways, the medicament being formulated in such a way that the peptide is delivered on the air side of the respiratory tract, namely to the apical membrane of the mucosal epithelial cells.
A medicament in a preparation which is delivered via the airways to the apical membrane, characterized in that it comprises at least one peptide which activates guanylate cyclase C.
A method for diagnosing disorders which are associated with impairments of ventilation and impairments of mucus secretion in the respiratory tract through detection of at least one peptide which activates guanylate cyclase C.
Dependencies are inferred from the claim text.