Detecting genetic predisposition to sight-threatening diabetic retinopathy
OwnerGordon Duff, Patrick Richardson +1inventors
InventorsGordon Duff, Patrick Richardson, Ian Rennie
Life of this patent
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Abstract
A method and kit for predicting increased risk of sight-threatening diabetic retinopathy which includes isolating genomic DNA from a sample from a diabetic patient. The genetic polymorphism pattern for the genes IL-1A, IL-1B and IL-1RN is then identified in the DNA. The identified pattern is compared with control patterns of known polymorphisms, and patients expressing a genetic polymorphism pattern associated with increased risk of sight-threatening diabetic retinopathy are identified.
Claims3
A kit for the identification of a diabetic patient's genetic polymorphism pattern at IL-1A, IL-1B(-511), and IL-1RN associated with increased risk of sight-threatening retinopathy, said kit comprising:
- a) DNA sample collecting means, and
- b) means for determining a genetic polymorphism pattern for IL-1A (-889), IL-1B(-511), and IL-1RN
Dependencies are inferred from the claim text.