Method for treating retroviral infections
AssigneeUNIROYAL CHEMICAL COMPANY, INC., a corporation of the State of Delaware
InventorsJohn A. Lacadie, James B. Pierce
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Abstract
Compositions and methods of treating a retroviral infection in an afflicted host and/or inhibiting replication of a retrovirus involve administering a therapeutically effective amount of the following compound of formula I: A—L—B (I) wherein A is a substituted or unsubstituted aryl compound, substituted or unsubstituted piperidyl, or substituted or unsubstituted thiopheneyl; L is sulfonyl, sulfinyl or thio; and B is a substituted or unsubstituted aromatic nitrogen containing heteroaryl compound; or pharmacologically acceptable acid-addition and base-addition salts thereof.
Claims4
A pharmaceutical composition useful for treating a retroviral infection by a retovirus selected from the group consisting of HIV, HCMV and HHV, in an afflicted host, comprising a therapeutically effective amount of the following compound:
- A—L—B
- or a pharmaceutically acceptable acid-addition and base-addition salt thereof;
- wherein:
- component A is a substituted or unsubstituted aryl functional group, substituted or unsubstituted piperidyl, or substituted or unsubstituted thiopheneyl;
- component L is sulfonyl, sulfinyl or thio;
- and,
- component B is a substituted or unsubstituted aromatic nitrogen containing heteroaryl functional group;
- and
- a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.