Bicyclic compounds as NR2B receptor antagonists

A compound of the formula (I):

• 16
• wherein
• R1 and R2 independently represent a hydrogen atom, a halogen atom, an alkyl group having from 1 to 6 carbon atoms, an alkoxy group having from 1 to 6 carbon atoms, a cyano group, an alkanoyl group having from 1 to 6 carbon atoms, a haloalkyl group having from 1 to 6 carbon atoms, or a haloalkoxy group having from 1 to 6 carbon atoms;
• X represents a covalent bond, an alkylene group having from 1 to 3 carbon atoms, an alkylene group having from 1 to 3 carbon atoms substituted by a hydroxy group or an oxo group;
• a methyleneoxy group, an ethyleneoxy group, a methyleneoxymethylene group, an oxymethylene group, an ethyleneoxy group, oxy, imino, iminomethylene, iminoethylene, methyleneimino or ethyleneimino, said imino groups are unsubstituted or are substituted by an alkyl group having from 1 to 6 carbon atoms;
• A represents a bicyclic, aromatic, saturated or partially unsaturated heterocyclic or carbocyclic group having from 8 to 12 ring atoms;
• said heterocyclic group contains either from 1 to 4 nitrogen atoms, or 1 or 2 nitrogen atoms and/or 1 or 2 oxgen or sulfur atoms,
• said heterocyclic or carbocyclic group are unsubstituted or are substituted by at least one substituent selected from the group consisting of substituents α;
• B represents a phenyl group or a heteroaryl group having from 5 to 6 ring atoms;
• said phenyl groups and said heteroaryl groups having from 5 to 6 atoms are unsubstituted or are substituted by at least one substituent selected from the group consisting of substituents α;
• said substituents a are selected from the group consisting of halogen atoms, alkyl groups having from 1 to 6 carbon atoms, alkoxy groups having from 1 to 6 carbon atoms, cyano groups, alkanoyl groups having from 1 to 6 carbon atoms, haloalkyl groups having from 1 to 6 carbon atoms, oxo groups or haloalkoxy groups having from 1 to 6 carbon atoms;
• or a pharmaceutically acceptable ester of such compound;
• or a pharmaceutically acceptable salt thereof.