Cytokine antagonist molecules
AssigneeAres Trading S.A.
InventorsAndrew Robert Davids, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Yolande Chvatchko, Ursula Boschert
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Abstract
This invention relates to a novel protein (INSP052), herein identified as an immunoglobulin domain-containing cell surface recognition molecule and to the use of this proteins and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease. The invention also relates to the identification of the extracellular domain of INSP052.
Claims77
A polypeptide, which polypeptide:
- i. comprises or consists of the amino acid sequence as recited in SEQ ID NO:
- 16 or SEQ ID NO:26;
- or
- ii. is a fragment of a polypeptide which comprises or consists of the amino acid sequence as recited in SEQ. ID NO:
- 16 or SEQ ID NO:26, having the activity of a polypeptide according to (i), or having an antigenic determinant in common with a polypeptide according to (i);
- or
- iii. is a functional equivalent of (i) or (ii).
A method of treating a disease in a patient, comprising administering to the patient a pharmaceutical composition of claim 66.
Dependencies are inferred from the claim text.