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US 2004/0176922 A1Published application
Method for calibrating spectrophotometric apparatus
OwnerJames Samsoondarinventor
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OwnerJames Samsoondarinventor
Estimating the term…
Described is a method for calibrating a spectrophometric apparatus. This method involves obtaining a first set of absorbance measurements of a set of calibrators on a First Apparatus that is in control at wavelengths from a first wavelength calibration table. A second wavelength calibration table on a second apparatus is established, wherein the first and the second wavelength calibration tables may be the same or different. A second set of absorbance measurements of the set of calibrators is obtained on the Second Apparatus, at wavelengths from the second wavelength calibration table. First and second interpolated absorbances are determined, for the first and the second absorbance measurement, respectively, for at least one wavelength of a Standard Set of Wavelengths. Using the first and the second interpolated absorbances, a linear regression equation for each wavelength of said Standard Set of Wavelengths is determined. The linear regression equation and at least one Primary Calibration Algorithm are incorporated onto the Second Apparatus, to produce a calibrated apparatus. The present invention is also directed to a medium storing instructions adapted to be executed by a processor to determine analyte concentration within a sample. Furthermore, the present invention provides an apparatus for determining analyte concentration of a sample, and a system for determining presence of an analyte in a sample.
A method for Calibration Algorithm Transfer comprising:
20 The method according to claim 19, wherein said standard set of wavelengths is obtained by:
32 The method according to claim 29, wherein said vessel is selected from the group consisting of a pipette tip, a labeled test tube, an unlabeled test tube, blood bag tubing, a transparent sample container, and a translucent sample container.
A method for Calibrating an apparatus comprising:
46 The method according to claim 42, wherein in said step of measuring (step (b)), said sample is any biological or non-biological fluid, and said analyte is any substance in said sample that can be measured.
69 A medium storing instructions adapted to be executed by a processor to determine analyte concentration within a sample as defined by the method of claim 27, said instructions comprising
71 A kit comprising said set of calibrators, said medium of claim 68, and instructions for use.
The kit of claim 71, wherein said set of calibrators are any type of calibrators suitable for producing one or more said first linear regression equations based on interpolated absorbances obtained using a first apparatus that is in control and interpolated absorbances obtained using a second apparatus.
A kit comprising said set of calibrators, said medium of claim 69, and instructions for use.
A system for determining presence of an analyte comprising
Dependencies are inferred from the claim text.