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US 2004/0176642 A1Published application
Process for preparing aminostilbene derivatives
AssigneeAjinomoto Co., Inc.
InventorsTakashi Yamamoto, Hiroyuki Matsueda, Masaki Naito, Isao Arai, Masanobu Yatagai
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Abstract
The present invention relates to a novel process for preparing an aminostilbene derivative, which is important as an active component of anticancer drugs or an intermediate for preparation thereof, as well as methods of producing the same.
Claims21
A method for preparing an aminostilbene derivative of formula (2):
- 7
- wherein each of R1, R2, R3 and R4 independently represents an alkyl group having 1-3 carbon atoms and the linking sites of OR4 and NH2 on the benzene ring are optional
- comprising
- reacting a nitrostilbene derivative represented by formula (1) with formic acid and/or a formate salt in the presence of a noble metal catalyst
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- wherein each of R1, R2, R3 and R4 independently represents an alkyl group having 1-3 carbon atoms and the linking sites of OR4 and NO2 on the benzene ring are optional.
3 more elements
Dependencies are inferred from the claim text.