Vitreoretinal silicone tamponades made by supercritical fluid extraction
AssigneeBausch & Lomb Incorporated
InventorsJay F. Kunzler, Joseph C. Salamone, Dharmendra Jani, Erik M. Indra
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Abstract
A process for the purification of a silicone oil or fluid using neat supercritical carbon dioxide or a supercritical carbon dioxide mixture extraction to produce vitreoretinal silicone tamponades. The subject process is an economical, highly effective, reproducible, contaminant-free method by which unreacted relatively low molecular weight cyclic siloxanes and oligomers are removed from relatively high molecular weight silicone oil or fluid.
Claims16
A process for the purification of silicone oil or fluid for use as an ocular tamponade comprising:
- performing a supercritical carbon dioxide extraction of said silicone oil or fluid to remove cyclic and oligomeric impurities.
A process for the purification of silicone oil or fluid for use as an ocular tamponade comprising:
- performing a supercritical carbon dioxide mixture extraction of said silicone oil or fluid to remove cyclic and oligomeric impurities.
Dependencies are inferred from the claim text.