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AssigneeRyoji Tamura
InventorsHiroaki Okamoto, Tsutomu Nishizawa
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By isolating a so far unknown novel hepatitis virus and determining the gene sequence thereof, genes, polynucleotides, polypeptides, methods for isolating virus particles, virus particles, and antiviral antibodies, which can be used for diagnosis and treatment, as well as methods for detecting viruses are provided. Disclosed is a non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence from which a sequence having a length of from about 3500 nucleotides to about 4000 nucleotides can be amplified by PCR utilizing an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 57 and an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 60 as primers, or PCR utilizing an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 57 and an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 61 as primers. Based on the nucleotide sequence of the gene, polypeptides etc. are provided.
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence from which a sequence having a length of from about 3500 nucleotides to about 4000 nucleotides can be amplified by PCR utilizing an oligonucleotide having a nucleotide sequence shown in SEQ ID NO:
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence from which a sequence having a length of from about 200 nucleotides to about 350 nucleotides can be amplified by PCR utilizing an oligonucleotide having a nucleotide sequence shown in SEQ ID NO:
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence from which a sequence having a length of from about 200 nucleotides to about 350 nucleotides can be amplified by PCR utilizing an oligonucleotide having a nucleotide sequence shown in SEQ ID NO:
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence shown in SEQ ID NO:
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence shown in SEQ ID NO:
A method for detecting a non-B, non-C, non-G hepatitis virus gene wherein PCR is performed by using an oligonucleotide having a nucleotide sequence shown in SEQ ID NO:
A method for detecting a non-B, non-C, non-G hepatitis virus gene wherein PCR is performed by using an oligonucleotide having a nucleotide sequence shown in SEQ ID NO:
A polypeptide comprising an amino acid sequence which is recognized in an amino acid sequence of SEQ ID NO:
A method for isolating non-B, non-C, non-G hepatitis virus particles wherein the non-B, non-C, non-G hepatitis virus particles are isolated based on density of the particles.
A recombinant gene expression vector which comprises all or a part of a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO:
A transformant cell containing all or a part of a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO:
A vaccine containing a polypeptide having an amino acid sequence contained in an amino acid sequence encoded by an opening reading frame present in a nucleotide sequence shown in SEQ ID NO:
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence shown in SEQ ID NO:
A non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence shown in SEQ ID NO:
A method for detecting a non-B, non-C, non-G hepatitis virus gene wherein PCR is performed by using an oligonucleotide having a nucleotide sequence shown in SEQ ID NO:
A polypeptide comprising an amino acid sequence which is recognized in an amino acid sequence of SEQ ID NO:
A recombinant gene expression vector which comprises all or a part of a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO:
A transformant cell containing all or a part of a nucleotide sequence encoding an amino acid sequence shown in SEQ ID NO:
A vaccine containing a polypeptide having an amino acid sequence contained in an amino acid sequence encoded by an opening reading frame present in a nucleotide sequence shown in SEQ ID NO:
Dependencies are inferred from the claim text.