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US 2004/0176350 A1Published application
Carbapenem compound
OwnerHiroshi Matsuiinventor
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Abstract
A carbapenem compound represented by the formula (I′): 1 wherein each symbol is as defined in the specification, and an antibacterial agent containing this compound as an active ingredient are provided. The carbapenem compound of the present invention is superior in absorbability from the gastrointestinal tract by oral administration and extremely useful for the prophylaxis or treatment of infectious diseases (particularly, bacterial infectious diseases).
Claims8
A carbapenem compound represented by the formula (I′):
- 20
- wherein
- R1is —CH2OCOC(CH3)3, —CH2OCO2CH(C2H5)2, —CH(CH3)OCO2CH(C2H5)2,
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- R2 is —CH2CH2CH3 or —CH2CH3, —CH(CH3)2,
- provided that (i) when R1 is —CH2OCOC(CH3)3, then R2 should be —CH2CH2CH3,
- (ii) when R1 is —CH2OCO2CH(C2H5)2 or —CH(CH3)OCO2CH(C2H5)2, then R2 should be —CH2CH2CH3, —CH2CH3 or —CH(CH3)2, and
- (iii) when R1 is
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- then R2 should be —CH2CH2CH3 or —CH(CH3)2.
7 more elements
A carbapenem compound represented by the formula (I):
- 23
Dependencies are inferred from the claim text.