Siglec inhibitors

Siglec inhibitor with the formula:

• 3
• whereby
• X signifies a negatively charged group such as a carboxy, phosphate or sulphate group or a derivative of them;
• Y signifies an H atom, an alkyl or aryl group, a hydroxy group, a glycan, a polymer carrier molecule or a derivative of them;
• Z is selected from O, N, C and S;
• R1 signifies an H atom, a hydroxy group or a derivative of them;
• R2 signifies a hydroxy or amino group or a derivative of them;
• R3 signifies a hydroxy group or a derivative of it;
• R4 signifies a hydroxy group or a derivative of it;
• R5 signifies a substituted or unsubstituted amino group, whereby the substituent is selected from a substituted or unsubstituted formyl, alkanoyl, cycloalkanoyl, aryl-carbonyl, heteroaryl-carbonyl, alkyl, aryl, cycloalkyl or heteroaryl group, whereby these residues can also include one or more unsaturated bonds, whereby R4 acts as H acceptor and R5 as H donor;
• R6 signifies an H atom or an alkyl group, a charged group or a derivative of them;
• R6′ signifies an H atom or an alky group, a charged group or a derivative of them, whereby at least one substituent is selected from R6 and R6′ is a hydrophobic group, preferably an H atom or a methyl group;
• and
• R7 signifies an H atom or any group, preferably a group for improving the pharmacological properties of the siglec inhibitor.