Bmp binding proteins for use in bone or cartilage regeneration
OwnerAndrew James Harrison, Andrea Jane Scully +2inventors
InventorsAndrew James Harrison, Andrea Jane Scully, Wendy Jane Mustill, Brian Mark Thomson
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Abstract
A medicament or device for tissue regeneration, for example bone and/or cartilage tissue, in which the medicament or device comprises a BMP binding protein.
Claims25
A pharmaceutical composition comprising a BMP binding protein.
A pharmaceutical composition comprising a BMP binding protein to aid tissue regeneration.
A pharmaceutical composition as claimed in any one of the preceding claims in which the BMP binding protein is selected from the group:
- follistatin, a protein described in the amino acid sequence (1) listed, or derivatives, fragments and/or analogues thereof.
Use of a BMP binding protein in the manufacture of a medicament for the treatment of diseases or clinical conditions that may be alleviated by the promotion of tissue regeneration e.g. cartilage and/or bone tissue regeneration.
A scaffold for promoting tissue generation in which the scaffold comprises a BMP binding protein.
A method of manufacturing a scaffold for promoting tissue generation comprising the step of:
- coating a scaffold with a BMP binding protein.
Dependencies are inferred from the claim text.