Flint glycoforms
OwnerNigel Jenkins, Derrick Ryan Witcher +1inventors
InventorsNigel Jenkins, Derrick Ryan Witcher, Victor John Wroblewski
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Abstract
The present invention provides FLINT isoforms having an average sialic acid content of 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0 or greater than 4.0 per molecule of FLINT. Also provided are mixtures of said isoforms, and methods for making said isoforms.
Claims16
A composition comprising FLINT isoforms said composition having an average sialic acid content of less than about 0.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 0.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 1.0 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 1.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 2.0 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 2.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 3.0 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 3.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 4.0 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 4.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 5.0 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 5.5 sialic acids per molecule of FLINT.
A composition comprising FLINT isoforms said composition having an average sialic acid content of about 6.0 sialic acids per molecule of FLINT.
A pharmaceutical composition comprising a therapeutically effective amount of a FLINT isoform and a pharmaceutically acceptable diluent, adjuvant or carrier.
Dependencies are inferred from the claim text.