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US 2004/0175812 A1Published application
Carbohydrates and polyols for dissolving protein crystals
OwnerSvend Kaasgaard, Kishore Rane +2inventors
InventorsSvend Kaasgaard, Kishore Rane, Michael Hess, Thomas Chambers Jr.
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Abstract
A method for recovering a protein of interest from a culture solution comprising: adding a polyol having the formula CnH2n+2On, wherein n is from 4 to 8, and/or a carbohydrate, and/or a derivative thereof, to the culture solution during recovery processing.
Claims18
A method for recovering a protein of interest from a culture solution comprising:
- adding a polyol having the formula CnH2n+2On, wherein n is from 4 to 8, and/or a carbohydrate, and/or a derivative thereof, to the culture solution during recovery processing.
A method for recovering a protein of interest from a culture solution comprising a recovery step in which step the protein of interest is in solution but above its solubility limit, comprising
- adding a carbohydrate, and/or a polyol and/or a derivative thereof, to the culture solution prior to, or immediately after, said recovery step.
Dependencies are inferred from the claim text.