Method of detecting PrPsc in eye fluid

Abstract

The invention provides novel methods of detecting PrPSc. More specifically, the invention provides novel methods of detecting PrPSc in eye fluid extracted from an eye globe of an animal. In contrast to previously known methods, the methods of the invention are readily performed on living animals, thereby facilitating the diagnosis of PrPSc-associated disease prior to death. The methods also feature the decreased presence of antigen-binding factors, which could block antibody-antigen interactions, as well as lower background PrPc.

Dependencies are inferred from the claim text.