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US 2004/0175699 A1Published application
Myocardium-specific promoter
OwnerMarc Fiszman, Bernard Prudhon +1inventors
InventorsMarc Fiszman, Bernard Prudhon, Yves Fromes
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Abstract
Myocardium-specific promoter derived from the MYBPC gene of a mammal and comprising the regulatory cis-elements necessary and sufficient to direct the specific expression of a gene in the myocardium. Use for treating myocardial diseases.
Claims11
Nucleic acid molecule capable of directing the specific expression of a gene in the myocardium, characterized in that it comprises the cis-elements for regulating transcription of the promoter of a mammalian MYBPC3 gene, which elements for regulating transcription comprise at least two binding sequences for a GATA-4 transcription factor.
Dependencies are inferred from the claim text.