Production of peptides in plants as viral coat protein fusions
AssigneeBiosource Technologies, Inc.
InventorsThomas H. Turpen, Stephen J, Reinl, Laurence K. Grill
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Abstract
The present invention relates to foreign peptide sequences fused to recombinant plant viral structural proteins and a method of their production. Fusion proteins are economically synthesized in plants at high levels by biologically contained tobamoviruses. The fusion proteins of the invention have many uses. Such uses include use as antigens for inducing the production of antibodies having desired binding properties, e.g., protective antibodies, or for use as vaccine antigens for the induction of protective immunity, including immunity against parasitic infections.
Claims13
A polynucleotide encoding fusion protein, the fusion protein consisting essentially of a tobamovirus coat protein fused to a protein of interest at a fusion joint.
Dependencies are inferred from the claim text.