Tissue harvesting device and method
AssigneeKCI Licensing, Inc.
InventorsAjit Mishra, Charles Seegert, Makoto Ohira
Life of this patent
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Abstract
A tissue harvesting method and device for obtaining micrograft tissue particles within the size range of 50-1500 microns, and more preferably 500-1000 microns, and most preferably 600 microns. The particles may be processed after a piece of donor tissue has been excised from the donor site, or processed into the desired size directly at the donor site, and thereafter excised. Cutters having blades or cutting edges spaced in the range of 50-1500 microns are utilized to obtain particles within the desired size range. An elastomer is positioned between the cutting edges to push the excised particles out of the blades for ease of use.
Claims51
A method of harvesting tissue for transplantation to a recipient site, comprising the steps of:
- (i) extracting a section of dermal tissue from a donor site;
- (ii) processing said tissue through a tissue cutter such that said tissue is processed in to particles of a size conducive for cell proliferation greater than about 6:1 and up to about 20:1;
- and
- (iii) mechanically retrieving said processed tissue from said cutter.
A method of harvesting tissue for transplantation to a recipient site, comprising the steps of:
- (i) applying a plurality of vertical cuts to a section of donor tissue at a donor site;
- and
- (ii) extracting a plurality of donor particles from said donor site by applying a horizontal cut along a connection point of said donor particles to said donor site and through said vertical cuts, such that said donor particles are of a size conducive for proliferation greater than about 6:1 and up to about 20:1;
- and
A cutter for processing tissue into particles suitable for transplantation, comprised of a cylindrical roller having a raised surface of evenly spaced perpendicularly arranged cutting edges.
A cutter for processing tissue into particles suitable for transplantation, comprised of a rigid sheet of raised cutting edges.
A cutter for processing tissue into particles suitable for transplantation, comprising:
- (i) a first cylindrical roller, having a first set of raised, parallel cutting edges;
- and
- (ii) a second roller having a second set of raised, parallel cutting edges;
- and
- (iii) wherein said first set of raised cutting edges is approximately perpendicular to said second set of raised cutting edges.
A cutter for processing tissue into particles suitable for transplantation, comprising a plurality of circular blades in parallel arrangement along a horizontal axis, and wherein said blades are adjustably secured to create a uniform distance between each circular blade.
A cutter for processing tissue into particles suitable for transplantation, comprising:
- (i) a housing;
- (ii) a cylindrical press movable within said housing from a closed distal end of said housing toward an open proximal end of said housing;
- (iii) an elastomer fixedly connected to said press;
- (iv) a removable cap positioned at said open proximal end of said housing;
- and
- (v) a plurality of blades fixedly connected within said housing, and interposed between said press and said open proximal end.
A cutter for processing tissue into particles suitable for transplantation, comprising:
- (i) a plurality of serrated discs, wherein said discs are slotted, and wherein said discs are fixedly positioned along an axis such that a space is created between said discs for receiving a tissue sample;
- (ii) a ring of longitudinal blades configured to pass between said serrations of said serrated discs.
Dependencies are inferred from the claim text.