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OwnerRobert Basic, Mirko Hadzija +1inventors
InventorsRobert Basic, Mirko Hadzija, Boris Subotic
Estimating the term…
The increased level of glucose in blood is the result of the destruction of β cells of the Islets of Langerhans by autoimmune process in insulin-dependent form of diabetes or a relative lack of insulin in insulin-dependent form of diabetes. Constantly present hyperglycemia in daibetes and a relative lack of insulin aid the development of the neuropathy as a late complication of diabetes. For that purpose, a technical problem was set before the inventor with the request of the reduction of glucose in blood, and stopping of the process of the development of the neuropathy as the consequence of the “long” duration of diabetes. Such a mineral-protein preparation was prepared by which glycemia was successfully regulated, but the process was also stopped by depositing of Ca+ in nerve cells. Those early changes caused by diabetes were successfully stopped, so that the appearance of the neuropathy, as a late complication in diabetes, was postponed. The mineral-protein preparation showed a hypoglycemia effect and stopped the development and progressing of the diabetic neuropathy.
The mineral-protein preparations, characterized by consisting of:
The mineral-protein preparation according to the request 1, characterized by the fact that the shares of particular components are as follows:
The mineral-protein preparation according to the request 2, characterized by the fact that the shares of particular components are as follows:
The mineral-protein preparation according to the requests 2-3, characterized by the fact that the synthetic zeolite was prepared by crystallization of the aluminosilicate hydrogel obtained by mixing of the alkaline solution of sodium aluminate and the alkaline solution of sodium silicate after which ionic exchange of the synthetic zeolite was carried out, during which Na+ ions were replaced with Ca2+ ions.
The mineral-protein preparation according to the request 4, characterized by the fact that the synthetic zeolite modified by procedures of ionic exchange contains instead of 7.2% -17.2% of Na+ ions, calculated as Na2O 6.5-15.6% Ca2+ ions calculated as CaO.
The mineral-protein preparation according to the request 5, characterized by the fact that the synthetic zeolite modified by procedures of ionic exchange contains:
The mineral-protein preparation according to the request 6, characterized by the fact that the calcium synthetic zeolite is 95-100% crystalline and without admixtures of other non-zeolite crystalline phases.
The mineral-protein preparation according to the request 6, characterized by the fact that the size of particles of the calcium synthetic zeolite ranges from 0.5 to 20 micrometers.
The mineral-protein preparation according to the request 6, characterized by the fact that the specific surface of the calcium synthetic zeolite is from 0.15 to 6 m3/g.
The mineral-protein preparation according to the requests 2-3, characterized by the fact that it contains protein fractions of the extract of plants obtained by the purification of the alcoholic extract of each particular plant component from the preparation on Sphadex G-25.
The mineral-protein preparation according to the requests 2-3, characterized by the fact that the source of the B-complex vitamins contained in the preparation is inactive yeast.
The mineral-protein preparation according to the request 11, characterized by the fact that inactive yeast is actually Saccharomices Sp.
The mineral-protein preparation according to the requests 2-3, characterized by the fact that it is prepared for per oral administration.
The mineral-protein preparation according to the requests 2-3, characterized by the fact that it is used for treatment of ill states connected with diabetes.
The mineral-protein preparation according to the request 14, characterized by the fact that it is used for preventing of neuropathies in mammals suffering from diabetes, including human beings.
The mineral-protein preparation according to the request 14, characterized by the fact that it reduces the concentration of GUK, reduces take of fluids into the organism, as well as the volume of excreted urine, inhibits the process of apoptosis in nerve cells and stops the process of creating of IgG on myelin fibres of nerve membranes, and eliminates the process of phagocytosis of apoptotic bodies.
The use of the mineral-protein preparation characterized by the fact that the preparation is used for treating of ill states connected with diabetes.
The use of the mineral-protein preparation according to the request 14, characterized by the fact that the preparation is used for reduction of the concentrated GUK, the reduction of taking fluids into the organism and the reduction of the volume of excreted urine, the inhibition of the process of apoptosis in nerve cells and stopping of the process of creating of IgG on myelin fibres of nerve membranes, as well as for the elimination of the process of phagocytosis of apoptotic bodies.
Dependencies are inferred from the claim text.