Omeprazole formulation
OwnerChih-Ming Chen, Joseph Chou +1inventors
InventorsChih-Ming Chen, Joseph Chou, Unchalee Kositprapa
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Abstract
A stable pharmaceutical composition of omeprazole for oral administration which consists essentially of: (a) a core of Omeprazole or a pharmaceutically equivalent salt, a filler and an alkaline material selected from the group consisting of lysing and arginine; and (b) a single layer of coating on said core which comprises a layer of an enteric coating agent which is applied from an organic solvent based system.
Claims11
A stable pharmaceutical composition of omeprazole for oral administration which consists essentially of:
- (a) a core of Omeprazole or a pharmaceutically equivalent salt, a filler and an alkaline material selected from the group consisting of lysine and arginine;
- and
- (b) a single layer of coating on said core which comprises a layer of an enteric coating agent applied from an organic solvent based system.
A pharmaceutical dosage formulation which consists essentially of:
- (a) a tablet core comprising omeprazole, a binder, an alkaline agent selected from the group consisting of arginine or lysine, a filler;
- and
- (b) an enteric coating agent around said core, said enteric coating comprising hydroxypropylmethyl cellulose phthalate and talc.
A pelleted pharmaceutical dosage formulation which consists essentially of:
- (a) a core comprising a non-pariel sugar seed coated with drug layer composition comprising omeprazole, a binder, an alkaline agent selected from the list consisting of arginine and -lysine, a filler and a surface active agent;
- and
- (b) an enteric coating agent around said core, said enteric coating comprising hydroxypropylmethyl cellulose phthalate and talc which is applied from an organic solvent based system.
Dependencies are inferred from the claim text.