Pharmaceutical compositions containing lipase inhibitors
AssigneeHoffmann-La Roche Inc.
InventorsPasschier Christiaan de Smidt, Paul Hadvary, Hans Lengsfeld, Thomas Rades, Hans Steffen, Joseph Tardio
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Abstract
A pharmaceutical composition comprises at least one inhibitor of lipases, preferably an inhibitor of gastrointestinal and pancreatic lipases, such as orlistat, at least one surfactant, and at least one dispersant.
Claims23
A pharmaceutical composition comprising (i) at least one lipase inhibitor, (ii) at least one non-ionic or zwitterionic surfactant selected from the group consisting of vitamin E polyethylene glycol 1000 succinate, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene stearates, polyoxyethylene alkyl ethers, polyoxyethylene castor oils, polyglycolyzed glycerides, transesterified and (poly)ethoxylated oils, sorbitan fatty acid esters, poloxamers, fatty acids salts, bile salts, alkylsulfates, lecithins, mixed micelles of bile salts and lecithins, sugar esters, and mixtures thereof., and (iii) at least one dispersant.
Dependencies are inferred from the claim text.