Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
AssigneeDePuy Mitek, LLC
InventorsIksoo Chun, Dennis D. Jamiolkowski, Kelly R. Brown, Julia Hwang, Francois Binette, Mora Carolynne Melican
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Abstract
A biocompatible tissue implant. The tissue implant may be bioabsorbable, and is made from a biocompatible polymeric foam. The tissue implant also includes a biocompatible reinforcement member. The polymeric foam and the reinforcement member are soluble in a common solvent.
Claims60
A tissue implant, comprising a biocompatible polymeric foam and a biocompatible polymeric reinforcement member, wherein the foam and the reinforcement member are soluble in a common solvent.
A method of manufacturing a biocompatible tissue implant, comprising:
- providing a solution comprising a foam forming, biocompatible polymer in a solvent, said solvent having a freezing point;
- providing a biocompatible polymeric reinforcement member;
- placing the polymeric reinforcement member in a cavity of a suitable mold;
- adding the solution to the cavity of the mold such that at least a part of the cavity is filled with the solution and at least part of the reinforcing member is in contact with the solution;
- quenching the reinforcement member and solution to below the freezing point of the solvent, and lyophilizing.
43 The method of claim 32, wherein the polymeric foam comprises a polymer selected from the group consisting aliphatic polyesters, poly(amino acids), polyalkylenes oxalates, polyamides, tyrosine derived polycarbonates, polyorthoesters, polyoxaesters, polyamidoesters, and copolymers and blends thereof.
A method of repairing damaged tissue, comprising:
- providing a biocompatible tissue implant comprising a biocompatible polymeric foam and a biocompatible reinforcement member, wherein the polymeric foam and the reinforcement member are soluble in the same solvent;
- and,
- placing the implant in a desired position at a site relative to a tissue injury.
Dependencies are inferred from the claim text.