Cyanoacrylate compositions for prophylactic or therapeutic treatment of diseases manifesting themselves in and/or damage cutaneous tissue
OwnerHans Brinch Lysterinventor
Life of this patent
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Abstract
A novel method for the prophylactic or therapeutic treatment of skin disorders and diseases by the application of a medicament that includes at least one cyanoacrylate compound. The medicament offers an advantageously novel alternative to hitherto known medicaments for the treatment of exanthemas, psoriasis exanthemas, and exanthemas in connection with fungal infections, as well as virus infections, and revision of infected and non-infected wounds.
Claims20
A method for treating exanthema on dermal or mucous membrane tissues, the method comprising:
- applying a sufficient amount of medicament onto a selected area of tissue, the medicament including a cyanoacrylate;
- and
- allowing the cyanoacrylate to polymerize and form a coat adhered to the selected area of tissue;
- wherein the cyanoacrylate has the general formula I:
- 3
- wherein R is chosen from the group of alkyls or alkenyls having 1 to 10 carbon atoms, cycloalkyls having 5 to 10 carbon atoms, phenyl, 2-ethoxyethyl, 3-methoxybutyl, arenes or alkyl-substituted arenes, or a substituent having the formula II:
- 4
- wherein R1 and R2 are chosen independently of each other from the group consisting of hydrogen, ethyl, propyl or butyl, and R″ is chosen from the group consisting of alkyls or alkenyls having 1 to 10 carbon atoms, cycloalkyls having 3 to 10 carbon atoms, phenyl, benzyl, methylbenzyl, phenylbenzyl, halogen-substituted or alkyl-substituted compounds thereof.
A method of treating a viral infection on dermal tissue or mucous membrane tissue, the method comprising:
- applying medicament onto an infected area of the tissue, the medicament including more than one cyanoacrylate, and an additive;
- allowing the cyanoacrylate to polymerize and form a coating on the infected area of tissue such that further development of the viral infection is inhibited, wherein the more than one cyanoacrylate has the general formula I:
- 5
- wherein R is chosen from the group of alkyls or alkenyls having 1 to 10 carbon atoms, cycloalkyls having 5 to 10 carbon atoms, phenyl, 2-ethoxyethyl, 3-methoxybutyl, arenes or alkyl-substituted arenes, or a substituent having the formula II:
- 6
- wherein R1 and R2 are chosen independently of each other from the group consisting of hydrogen, ethyl, propyl or butyl, and R″ is chosen from the group consisting of alkyls or alkenyls having 1 to 10 carbon atoms, cycloalkyls having 3 to 10 carbon atoms, phenyl, benzyl, methylbenzyl, phenylbenzyl, halogen-substituted or alkyl-substituted compounds thereof.
A method for revising a wound located on dermal or mucous membrane tissue, the method comprising:
- applying a sufficient amount of a cyanoacrylate to penetrate into cavities of the a crust of the wound;
- allowing the cyanoacrylate to polymerize and adhere to the crust;
- removing the crust adhered to the polymerized cyanoacrylate by pulling the cyanoacrylate from the dermal or mucous membrane tissue.
A method for removing at least a portion of a wart or condyloma from dermal tissue, the method comprising:
- applying a sufficient amount of a cyanoacrylate to at least partially encapsulate the wart or condyloma;
- allowing the cyanoacrylate to polymerize;
- removing at least a portion of the wart or condyloma which is at least partially encapsulated within the polymerized cyanoacrylate by pulling the cyanoacrylate from the dermal tissue.
A method for maintaining in close proximity separated tissue edges of a wound site during a tissue closure procedure, the method comprising:
- applying a sufficient amount of cyanoacrylate at the separated edges of a wound site such that gripping flaps are formed;
- allowing the cyanoacrylate to cure;
- and
- grasping the gripping flaps to place the edges of the wound in close proximity to facilitate the tissue closure procedure.
Dependencies are inferred from the claim text.