Rad51 polypeptides and uses thereof
AssigneePioneer Hi-Bred International, Inc.
InventorsPramod B. Mahajan, Jinrui Shi
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Abstract
The invention provides isolated RAD51C nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering RAD51C levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
Claims11
An isolated polypeptide comprising an amino acid sequence having at least 80% sequence identity to over the entire length of SEQ ID NO:
- 2, wherein the percent sequence identity is determined by GAP algorithm under default parameters, wherein the amino acid sequence encodes a polypeptide which specifically binds XRCC3.
An isolated polypeptide comprising SEQ ID NO:
- 2.
An isolated polypeptide comprising an amino acid sequence having at least 80% sequence identity to over the entire length of SEQ ID NO:
- 2, wherein the percent sequence identity is determined by GAP algorithm under default parameters, wherein the amino acid sequence encodes a polypeptide which forms part of a recombinosome.
An isolated antibody which is specifically reactive to a Rad51C polypeptide, wherein the antibody is produced using a polypeptide comprising at least 20 contiguous amino acids of SEQ ID NO:
- 2 as an antigen.
An isolated polypeptide wherein:
- (a) the isolated polypeptide comprises at least 20 contiguous amino acids of SEQ ID NO:
- 2;
- (b) the isolated polypeptide, when presented as an immunogen, elicits the production of an antibody which specifically binds to the polypeptide of SEQ ID NO:
- 2;
- and
- (c) the isolated polypeptide does not bind to antisera raised against the polypeptide of SEQ ID NO:
- 2 after the antisera has been fully immunosorbed with the polypeptide of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.