Back to results
US 2004/0171801 A1Published application
Nk-2 homeobox transcription factor
AssigneeMerck Patent GmbH
InventorClaudia Wilm
Life of this patent
Estimating the term…
Abstract
Nkx2-C4 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Nkx2-C4 polypeptides and polynucleotides in diagnostic assays.
Claims11
An polypeptide selected from one of the groups consisting of:
- (a) a polypeptide encoded by a polynucleotide comprising the sequence of SEQ ID NO:
- 1 or SEQ ID NO:
- 3;
- (b) a polypeptide comprising a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO:
- 2;
- or SEQ ID NO:
- 4
- (c) a polypeptide having at least 95% identity to the polypeptide sequence of SEQ ID NO:
- 2 or SEQ ID NO:
- 4;
- and
- (d) the polypeptide sequence of SEQ ID NO:
- 2 or SEQ ID NO:
- 4 and
- (e) fragments and variants of such polypeptides in (a) to (d).
12 more elements
A polynucleotide selected from one of the groups consisting of:
- (a) a polynucleotide comprising a polynucleotide sequence having at least 95% identity to the polynucleotide sequence of SEQ ID NO:
- 1 or SEQ ID NO:
- 3;
- (b) a polynucleotide having at least 95% identity to the polynucleotide of SEQ ID NO:
- 1 or SEQ ID NO:
- 3;
- (c) a polynucleotide comprising a polynucleotide sequence encoding a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO:
- 2 or SEQ ID NO:
- 4;
- (d) a polynucleotide having a polynucleotide sequence encoding a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO::
- 2 or SEQ ID NO:
- 4;
- (e) a polynucleotide with a nucleotide sequence of at least 100 nucleotides obtained by screening a library under stringent hybridization conditions with a labeled probe having the sequence of SEQ ID NO:
- 1 or SEQ ID NO:
- 3 or a fragment thereof having at least 15 nucleotides;
- (f) a polynucleotide which is the RNA equivalent of a polynucleotide of (a) to (e);
- or a polynucleotide sequence complementary to said polynucleotide
- and polynucleotides that are variants and fragments of the above mentioned polynucleotides or that are complementary to above mentioned polynucleotides, over the entire length thereof.
15 more elements
Dependencies are inferred from the claim text.