Screening method using solid supports modified with self-assembled monolayers
OwnerPierre Desreumaux, Sebastien Dharancy +1inventors
InventorsPierre Desreumaux, Sebastien Dharancy, Johan Auwerx
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Abstract
The invention concerns a screening method of a compound modulating the activity of a nuclear RXR-receptor heterodimer, preferably RXR-PPAR. The invention also concerns the compound capable of being selectively hybridised with the gene or a product of the gene coding for the RXR and PPAR subunits of said heterodimer, for preparing a medicine for preventive and/or curative treatment of an infection by the hepatitis C virus, or of fatty liver, of liver inflammation, liver lesions, liver cirrhosis, post-hepatic cancer whether or not associated with a hepatitis C virus infection.
Claims21
The use of a compound modulating the activity of an RXR-nuclear receptor heterodimer, for preparing a medicinal product intended for the preventive and/or curative treatment of an infection with a virus which uses, in order to perform its viral cycle, at least one cellular protein encoded by a gene which has at least one RE regulatory sequence.
Dependencies are inferred from the claim text.