L-ascorbic acid-2-o-maleic acid-a-tocopherol diester 1-propanol adduct and process for producing the same
AssigneeSenju Pharmaceutical Co., Ltd.
InventorsKazumi Ogata, Noriko Saito, Kazuhiko Yamada, Genta Maruyama
Life of this patent
Estimating the term…
Abstract
L-Ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt; cosmetic components, antioxidants, radical scavengers, anti-inflammatory agents and elastase inhibitors containing the same as the active ingredient; and a process for producing the above-described adduct characterized by comprising extracting a solution containing L-ascorbic acid-2-O-maleic acid-α-tocopherol diester with a solvent, distilling off the solvent, and adding to the residue 1-propanol mixed with an organic solvent followed by crystallization.
Claims11
L-Ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salts.
L-ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct in the crystalline form.
A process for producing L-ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct, characterized in that said process comprises subjecting a solution containing L-ascorbic acid-2-O-maleic acid-α-tocopherol diester to extraction with an extraction solvent, and adding 1-propanol or a solution mixture of 1-propanol with an organic solvent to the residue produced after distilling off the extracting solvent to thereby allow crystallization.
A composition, characterized in that said composition comprises L-ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt.
A cosmetic composition, characterized in that said composition comprises L-ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt.
An antioxidant composition, characterized in that said composition comprises L-Ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt.
A radical scavenging composition, characterized in that said composition comprises L-Ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt.
An anti-inflammatory composition, characterized in that said composition comprises L-ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt.
An elastase inhibitory composition, characterized in that said composition comprises L-ascorbic acid-2-O-maleic acid-α-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt.
Dependencies are inferred from the claim text.