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US 2004/0171650 A1Published application
Novel anthelmintic and insecticidal compositions
OwnerByung Hyun Lee, Martha Jane Larsen +1inventors
InventorsByung Hyun Lee, Martha Jane Larsen, Teresa Maria Kubiak
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Abstract
The present invention relates to novel anthelmintic and insecticidal compositions in general, and, more specifically, compositions containing triazole derivatives as active ingredients.
Claims6
A compound of Formula I
- 13
- wherein:
- R1, R2 and R4 are independently selected from the group H, C1-C8 alkyl, phenyl, substituted phenyl, benzyl, substituted benzyl, heteroaryl, substituted heteroaryl, hetroarylmethylene, and substituted hetroarylmethylene;
- R3 is H, C1-C8 alkyl, heteroalkyl, cycloalkyl, aryl, heteroaryl;
- with the proviso that the compound is not:
- 1-(4-methoxyphenyl)-2-[(4-phenyl-5-pyridin-4-yl-4H-1,2,4-triazol-3-yl)thio]ethanone (6);
- 1-(4-chlorophenyl)-2-[(4-phenyl-5-pyridin-4-yl-4H-1,2,4-triazol-3-yl)thio]ethanone (7);
- 1-(4-fluorophenyl)-2-[(4-phenyl-5-pyridin-4-yl-4H-1,2,4-triazol-3-yl)thio]ethanone (11);
- 1-phenyl-2-[(4-phenyl-5-pyridin-4-yl-4H-1,2,4-triazol-3-yl)thio]ethanone (12);
- 2-{[5-(4-methylphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}-1-phenylethanone (21);
- 1-(4-methoxyphenyl)-2-{[5-(4-methoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]thio}ethanone (27);
- or
- 1-(4-methoxyphenyl)-2-{[4-(4-methylphenyl)-5-pyridin-4-yl-4H-1,2,4-triazol-3-yl]thio}ethanone (39).
10 more elements
The method of treating parasitism by insects or helminths comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a pharmaceutically acceptable salt thereof.
A composition containing a compound of Formula I
- 14
- wherein:
- R1, R2 and R4 are independently selected from the group H, C1-C8 alkyl, phenyl, substituted phenyl, benzyl, substituted benzyl, heteroaryl, substituted heteroaryl, hetroarylmethylene, and substituted hetroarylmethylene;
- R3 is H, C1-C8 alkyl, heteroalkyl, cycloalkyl, aryl, heteroaryl.
1 more element
Dependencies are inferred from the claim text.