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US 2004/0171640 A1Published application
Substituted 1-phenethylpiperidine compounds used as inter alia analgesics
OwnerBernd Sundermann, Lambert Hoenen +3inventors
InventorsBernd Sundermann, Lambert Hoenen, Helmut Buschmann, Babette-Yvonne Koegel, Elmar Friderichs
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Abstract
The invention relates to substituted 1-Phenethylpiperidine compounds, a method for the production thereof, medicaments containing said compounds and the use of said compounds in the production of medicaments. 1
Claims24
Substituted 1-phenethylpiperidine compounds of the general formula I
- 13
- in which
- X denotes a methylene (CH2) or carbonyl (C═O) group,
- R1 denotes an optionally at least mono-substituted aryl or heteroaryl residue,
- R2 denotes H, COR5, SO2R5, an optionally at least mono-substituted, saturated, branched or unbranched aliphatic C1-10 residue, an optionally at least mono-substituted, at least mono-unsaturated, branched or unbranched aliphatic C2-10 residue, an optionally at least mono-substituted, saturated or at least mono-unsaturated cycloaliphatic C3-8 residue, an optionally at least mono-substituted aryl or heteroaryl residue or an optionally at least mono-substituted aryl or heteroaryl residue attached via a C1-3 alkylene group,
- R3 and R4 each separately denote H or together denote a bond,
- R5 denotes an optionally at least mono-substituted, saturated, branched or unbranched aliphatic C1-10 residue, an optionally at least mono-substituted, at least mono-unsaturated, branched or unbranched aliphatic C2-10 residue, an optionally at least mono-substituted, saturated or at least mono-unsaturated cycloaliphatic C3-8 residue, an optionally at least mono-substituted aryl or heteroaryl residue or an optionally at least mono-substituted aryl or heteroaryl residue attached via a C1-3 alkylene group,
- as a free base or a corresponding physiologically acceptable salt and corresponding racemates, enantiomers and diastereomers.
5 more elements
Dependencies are inferred from the claim text.