Back to results
US 2004/0171631 A1Published application
Orally administered analgesic compositions containing nalbuphine
OwnerOliver Yoa-Pu Hu, Cheng-Huei Hsionginventors
Life of this patent
Estimating the term…
Abstract
The present invention provides orally administered pharmaceutical compositions which contains an effective amount of free base or pharmaceutically acceptable salts of nalbuphine and/or nalbuphine ester, an oily substance, and a solubility-assisting agent. The oily substance is preferably sesame oil. The solubility-assisting agent is preferably benzyl benzoate. The pharmaceutical composition is useful as an analgesic. The compositions achieves a much higher bioavailability rate and yields much longer lasting effects on nalbuphine than other nalbuphine products currently in the market.
Claims17
A pharmaceutical composition comprising:
- as an active ingredient, an effective amount of free base or pharmaceutically acceptable salts of nalbuphine or nalbuphine ester;
- an oily substance;
- and
- a solubility-assisting agent;
- wherein said pharmaceutical composition is an orally administered composition.
2 more elements
Dependencies are inferred from the claim text.