Therapeutic agent for non-immediate type allergic diseases
AssigneeJapan Tobacco Inc.
InventorsHiroyuki Iwamura, Yoshifumi Ueda
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AssigneeJapan Tobacco Inc.
InventorsHiroyuki Iwamura, Yoshifumi Ueda
Estimating the term…
An objective of the present invention is to provide novel therapeutic agents for non-immediate-type allergic diseases that comprise, as an active ingredient, a cannabinoid receptor modulator, particularly that selectively acts on peripheral cell type cannabinoid receptors (CB2), and more particularly an inverse agonist. The present invention provides therapeutic agents for non-immediate-type allergic diseases which comprises a cannabinoid receptor modulator, particularly an inverse agonist that selectively acts on peripheral cell type cannabinoid receptors, specifically N-(benzo[1,3]dioxol-5-yl methyl)-7-methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3-carboxamide or such, or pharmaceutically acceptable salt thereof. The therapeutic agents of the present invention are effective, for example, against intractable allergic diseases, such as asthma and atopic dermatitis.
A therapeutic agent for a non-immediate-type allergic disease, which comprises as an active ingredient an inverse agonist of the peripheral cell type cannabinoid receptor.
A method for identifying a candidate compound for a therapeutic agent for a non-immediate-type allergic disease, which comprises the steps of:
A method for identifying a candidate compound for a therapeutic agent for a non-immediate-type allergic disease, which comprises the steps of:
A method for treating a non-immediate-type allergic disease, which comprises administering a preparation containing an effective amount of CB2 inverse agonist to a patient affected with the non-immediate-type allergic disease.
A therapeutic agent for a disease associated with 2-AG and/or 2-AG-E, which comprises as an active ingredient an inverse agonist of the peripheral cell type cannabinoid receptor.
Dependencies are inferred from the claim text.