Pyridines for treating injured mammalian nerve tissue

A compound according to formula (I):

• 8
• or a pharmaceutically acceptable salt, solvate, or polymorph thereof, wherein R1 is H or a C1-C4 alkyl group;
• 9
• 10
• R3 is H, a C1-C20 alkyl group, an OR group, an alkylene ester group
• 11
• an amine group —NR11R12 or a —(CH2)m═ group where m is 1-3 and forms a ring with R6, R is a C1-C20 alkyl group, an aryl group or an alkylene aryl group, R10 is a C1-C10 alkyl group, n is 1 to 20, R11 is selected from H, C1-C4 alkyl, aryl, alkylene aryl or an alkylene ester group as described above, and R12 is selected from H, C1-C4 alkyl, aryl, alkylene aryl or an alkylene ester group as described above or is a —(CH2)z-group where z is 0 to 2, such that R12 forms a ring with R6, and wherein when one of R11 and R12 is other than H, the other of R11 or R12 is H;
• R6 is H, C1-C4 alkyl, F, Cl, Br, I, NO2 or a NR13R14 group where R13 is H or a C1-C3 alkyl group and R14 is a —(CH2)m- group where m is 0 to 3 and forms a ring with the
• 12
• group when R3 is absent;
• and each of R7, R8 and R9 is independently selected from H, C1-C4 alkyl, F, Cl, Br, I or NO2, preferably, at least two, and more preferably three of R7, R8 and R9 are H.