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US 2004/0171569 A1Published application
Artificial chromosome constructs containing foreign nucleic acid sequences
OwnerBrian Horsburgh, Dong Qiang +2inventors
InventorsBrian Horsburgh, Dong Qiang, Francis Tufaro, Jeffrey Ostrove
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Abstract
The invention provides artificial chromosome constructs containing foreign nucleic acid sequences, such as viral nucleic acid sequences, and methods of using these artificial chromosome constructs for therapy and recombinant virus production.
Claims20
An artificial chromosome construct comprising a nucleic acid sequence that directs formation of a recombinant virus upon introduction into a cell.
A cell comprising an artificial chromosome construct stably integrated into its genome.
Dependencies are inferred from the claim text.