Topical formulations for treatment of rosacea
OwnerKarl F. Poppinventor
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Abstract
Methods of using a topical composition comprising a storage-stable mixture of a benzoyl peroxide dispersion and clindamycin or pharmaceutically acceptable salts or esters thereof for treating rosacea. These methods also contemplate the reduction or elimination of Demodex folliculorum organisms from affected skin areas, thereby reducing clinical signs of rosacea potentially due to allergic and vasomotor responses of the body to the organism in susceptible persons.
Claims57
A method for treating rosacea in a patient, comprising:
- topically administering to a patient in need thereof a topical composition in an amount effective to treat said rosacea, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating rosacea.
A method for reducing or eliminating mite organisms that cause rosacea in a patient, comprising:
- topically administering to skin of a patient infected with said mite organisms a topical composition in an amount effective to reduce or eliminate said mite organisms, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in reducing or eliminating said mite organisms.
A method for treating rosacea in a patient having sensitive skin, comprising:
- topically administering to sensitive skin areas, irritated skin areas, or inflamed skin areas of a patient in need thereof a topical composition in an amount effective to treat said rosacea, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier;
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating rosacea.
A method for treating rosacea in a patient, comprising:
- topically administering to a patient in need thereof a topical composition in an amount effective to treat said rosacea, wherein said composition comprises:
- a storage-stable mixture of a benzoyl peroxide dispersion, clindamycin or a pharmaceutically acceptable salt or ester thereof, and a pharmaceutically acceptable carrier,
- wherein said topical composition has a viscosity that enhances the effectiveness of the topical composition in treating rosacea;
- and wherein said topical composition is administered concomitantly or sequentially with an additional active agent effective to treat said rosacea.
Dependencies are inferred from the claim text.