Method of inhibiting angiogenesis or invasion or formation of metastases
AssigneeINSERM, a corporation of France
InventorsVeronique Trochon, He Lu, Claudine Soria
Life of this patent
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Abstract
A method of inhibiting angiogenesis or invasion or formation of metastases in a mammal including administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance including all or part of a disintegrin domain of an adamalysin or a derivative thereof, a nucleic acid molecule including a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
Claims12
A method of inhibiting angiogenesis or invasion or formation of metastases in a mammal comprising administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance comprising all or part of a disintegrin domain of an adamalysin or a derivative thereof, a nucleic acid molecule comprising a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
A method of treating cancer in a mammal comprising administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance comprising all or part of a disintegrin domain of an adamalysin or a derivative thereof and a nucleic acid molecule comprising a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
A method of treating inflammatory diseases in a mammal comprising administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance comprising all or part of a disintegrin domain of an adamalysin or a derivative thereof and a nucleic acid molecule comprising a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
A method of treating atherosclerosis in a mammal comprising administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance comprising all or part of a disintegrin domain of an adamalysin or a derivative thereof and a nucleic acid molecule comprising a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
A method of treating macular degeneration in a mammal comprising administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance comprising all or part of a disintegrin domain of an adamalysin or a derivative thereof and a nucleic acid molecule comprising a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
A method of treating psoriasis in a mammal comprising administering a therapeutically effective amount of an active agent selected from the group consisting of a protein substance comprising all or part of a disintegrin domain of an adamalysin or a derivative thereof and a nucleic acid molecule comprising a polynucleotide sequence coding all or part of the disintegrin domain of an adamalysin or a derivative thereof to the mammal.
Dependencies are inferred from the claim text.