Method of treatment of conditions by administration of streptolysin O
AssigneeMilkhaus Laboratory, Inc.
InventorsJohn McMichael, Jean-Frederic Sauniere
Life of this patent
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Abstract
Method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.
Claims47
A method of alleviating symptoms of a connective tissue disorder selected from the group consisting of Dupuytren's contracture, scleroderma, Peyronie's disease, and claudication due to peripheral arterial disease comprising administering to a subject in need thereof, streptolysin O in an amount effective to treat one or more symptoms of said connective tissue disorder.
The method of alleviating symptoms of a connective tissue disorder in bovines which is mastitis comprising administering to a bovine in need thereof streptolysin O in an amount effective to treat one or more symptoms of said connective tissue disorder.
A pharmaceutical composition for administering to a subject for alleviating symptoms of a connective tissue disorder selected from the group consisting of Dupuytren's contracture, sclerodemia, Peyronie's disease, and claudication due to peripheral arterial disease comprising streptolysin O in an amount effective to treat one or symptoms of said connective tissue disorder in a pharmaceutically acceptable excipient.
A pharmaceutical composition for administering to a bovine for alleviating symptoms of a connective tissue disorder selected from the group consisting of mastitis due comprising streptolysin O in an amount effective to treat one or more symptoms of said connective tissue disorder in a pharmaceutically acceptable excipient.
A method of alleviating symptoms of reproductive fibrosis conditions comprising administering to a subject in need thereof, streptolysin O in an amount effective to treat one or more symptoms of said reproductive fibrosis.
A method of protecting nerve cells in a subject from the effects of neurotoxic agents comprising administering to said cells an effective amount of Streptolysin O.
A method of inhibiting CD44 receptor mediated processes comprising administering streptolysin O to cells expressing the CD44 receptor in an amount effective to inhibit said CD44 receptor mediated processes.
Dependencies are inferred from the claim text.