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AssigneeLegere Pharmaceuticals, Ltd.
InventorsHoward C. Krivan, Richard C. Potter, Michael J. Oldham
Estimating the term…
Infectious diseases caused by pathogenic microorganisms resident in the alimentary tract of humans and animals can be prevented and treated by administering to the alimentary tract of the human or animal an effective amount of a composition containing at least one lectin capable of binding to an infective microorganism and diminishing its infective capability of the microorganism. The lectin is administered dispensed in a pharmaceutically acceptable non-toxic vehicle. Peptic ulcer disease caused by infection with H. pylori can be treated by oral administration of lectins that bind to the pathogen. A beneficial ecology of H. pylori! can be maintained in infected patients by chronic oral administration of lectins that bind to the pathogen.
A method of preventing and/or treating infectious diseases caused by pathogenic microorganisms resident in the alimentary tract or nasal cavity of humans and animals comprising administering to the alimentary tract or nasal cavity of a human or animal an amount of a composition containing at least one lectin capable of binding to an infective microorganism resident in said alimentary tract or nasal cavity, said lectin being effective to diminish the infective capability of said microorganism, said lectin being dispersed in a pharmaceutically acceptable non-toxic vehicle.
A method of preparing a concentrated dosage form of WGA lectin comprising separating a wheat germ into fractions and selecting a fraction having an activity of WGA greater than that of said wheat germ prior to said separation.
An oral dosage form containing WGA comprising a fraction separated from a wheat germ, said fraction having a higher activity of WGA than said wheat germ prior to separation.
Dependencies are inferred from the claim text.